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Here are the best vitamin B12 injection sites for each method: Subcutaneous B12 injection sites Usually, the best places to give yourself a B12 shot subcutaneously are the abdomen, thigh, and upper arm, as you can see in this illustration: Although not shown above, the buttock is another good site for B12 shots

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Actual costs may differ from figures mentioned in this publication due to individual protocol requirements, dosing specifications, or program updates

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However, some people may experience mild digestive changes when starting a new routine