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The JAK2/STAT3 and ERK pathways were involved in the possible molecular mechanism

These numbers are unprecedented for a non-surgical, pharmacological intervention and notably the weight-loss curve had not fully plateaued at 48 weeks, suggesting that even greater reductions might occur with longer exposure

It only affects new melanogenesis and not pre-existing pigmentation

Protena adicionada, reduo de acar, aumento do teor de fibras e fortificao nutricional passam a integrar estratgias estruturais de inovao