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Sikiric et al., 1997b

CD8+ T cells can downregulate the expression of SLC7A11, inhibit the glutamate-cysteine cycle, and reduce cysteine uptake in tumor cells, thereby promoting lipid peroxidation and ferroptosis [7]

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Clinical studies have found that both minimizing biomechanical forces on the eye during phacoemulsification and maximizing the removal of peripheral lens material (cortical cleanup) reduce short term PCO rates, perhaps by reducing the stimuli that can drive persistent tissue inflammation following surgery (see below) (5963)

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