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Ferreira JP, Sharma A, Butler J, et al
Regulation of growth hormone secretion
The CONQUER trial (Gadde et al., 2011) enrolled over 2,400 adults with obesity and at least two weight-related comorbidities, demonstrating that participants receiving the higher-dose combination (phentermine 15 mg/topiramate 92 mg) achieved mean weight loss of approximately 910% of baseline body weight at 56 weeks, compared to 12% with placebo
For details on insurance coverage criteria and challenges with compounded GLP-1s, see this Harvard Medical School perspective
Abstract Estimates suggest that there are currently 122.8 million adults 6599 years of age living with diabetes, of whom 9095% are diagnosed with type 2 diabetes (T2D)
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