A: The exact neurochemical effects that Contrave has towards weight loss have not yet been fully understood
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The combination produces greater weight loss than GLP-1 agonism alone
The medication lowers blood sugar by increasing insulin production and lowering glucagon secretion, curbs appetite and allows people to lose weight by eating less
da Silva Dias IC, Carabelli B, Ishii DK, de Morais H, de Carvalho MC, Rizzo de Souza LE, Zanata SM, Brando ML, Cunha TM, Ferraz AC, Cunha JM, Zanoveli JM (2016) Indoleamine-2,3-dioxygenase/kynurenine pathway as a potential pharmacological target to treat depression associated with diabetes