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Glucagon-like peptide-1 agonists in cardiovascular diseases: a bibliometric analysis from inception to 2023

They can also cause cramping and electrolyte imbalances, which can be problematic for individuals on long-term GLP-1 treatment

Individuals consuming under 1,000 kcals/d likely function in a catabolic state and the protein-sparing effect of carbohydrates is lost

Component of a mommy makeover: Lots of women pair it with breast surgery or liposuction for complete makeover

Median direct R&D cost: $150 million (median: the value that falls exactly in the middle when all values in a dataset are arranged from smallest to largest) Average direct R&D cost: $369 million After adjustments (for opportunity costs and drugs that did not reach the market): Median: $708 million, Average: $1.3 billion When only two extremely costly drugs are excluded, the average cost drops to $950 million (26% lower)