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[6] Because NAD + -dependent enzymes are involved in DNA repair, protein deacetylation, stress responses, mitochondrial function, and cellular signaling, NNMT-related changes in NAD + availability should be interpreted in a pathway-specific manner rather than as a simple beneficial-or-harmful binary

Inositol, Choline, Methionine, Thiamine (B1), Riboflavin (B2), Pyridoxine (B6), L-Carnitine

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In the foundational cell experiments, 5-Amino-1MQ reduced intracellular 1-methylnicotinamide in adipocyte-related systems