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TPN, in which all nutrition is delivered intravenously, is frequently associated with rapid weight loss and lack of gallbladder stimulation, both of which can contribute to gallstone formation (Shaffer 2018)
Because absorption is limited, raising serum B12 with pills is a gradual, cumulative process that can take weeks or months of consistent daily use
In fact, taking them as a pair is often more effective than taking either one alone
Int J Mol Sci 25(22):11955
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