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Matek D, Matek I, Staresinic E, Japjec M, Bojanic I, Blagai B et al
The daily dosage should not be ingested all at once but divided into 2 to 3 doses, spread over the day
The fact that the double-cysteine mutations only partially abolish the physiological function may imply that not all the expressed mutants have an intact disulfide bridge and that the observed conformation is only one possible inactive state on the cell surface, as supported by the EM data and MD simulations below
Ions were introduced to the mass spectrometer using an Easy-Spray source operating at 2 kV
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, compared with the sulfonylurea, glipzide, in patients with type 2 diabetes inadequately controlles on metformin alone: a randomized, double-blind, non-inferiority trial
