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AstraZeneca said the Phase 1 data so far show a differentiating clinical profile with good tolerability and encouraging glucose and body weight reduction across the dose levels tested compared to placebo. The company had its own GLP-1 agonist in Phase 1 testing for diabetes, but discontinued it earlier this year as part of a strategic portfolio prioritization. It has another in testing for non-alcoholic steatohepatitis.

One thing that we have learned in this time is that hair loss is one of the most misunderstood and undertreated conditions out there

There are mounting reports on the effects of intestinal microbial metabolites on human health

No published case reports document permanent allodynia from semaglutide or tirzepatide use

It may boost the production of nitric oxide, which improves blood flow