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If the side effects are too intense, the patient may need to continue taking the lower dosage for longer or may need to consider switching to a different medication or other weight loss alternatives
For active, high-output lifestyles
NICE guidance including Technology Appraisal TA875 (semaglutide 2.4 mg for managing overweight and obesity), Clinical Guideline CG189 (Obesity: identification, assessment and management), and Public Health Guidance PH53 (Weight management: lifestyle services for overweight or obese adults) recommends a structured, tiered approach to weight management
Weight loss and blood sugar improvements may temporarily plateau or fluctuate during the adjustment period
Injecting into skin that's bruised, scraped, scaly, dry, or tender may increase your risk of an injection site reaction
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