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One possible alternative is medication that acts simultaneously on several receptors as so-called multifunctional agonists
Many clinicians actively recommend PPI therapy for semaglutide users with significant reflux symptoms
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Despite GIP-R agonism having been linked to enhanced glucagon levels [40], treatment with all doses tirzepatide have surprisingly been associated with significantly reduced levels of fasting glucagon more than placebo [76] and dulaglutide [74]
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