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Hereditary defects in production of the transcobalamins and their receptors may produce functional deficiencies in B12 and infantile megaloblastic anemia, and abnormal B12 related biochemistry, even in some cases with normal blood B12 levels

Emerging evidence indicates that pulmonary surfactant not only facilitates respiration but also contributes to host defense by promoting pathogen clearance and immune modulation (Han and Mallampalli, 2015)