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It is useful in treating dyskinesias, although it has been shown to be ineffective for the treatment of motor fluctuations

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Because Ipamorelin does not meaningfully spike cortisol or prolactin at documented research doses, the protocol tends to emphasize pulse timing (getting the GH burst to land at a useful moment, such as during early sleep) rather than aggressive dose escalation

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Long-term studies have shown particularly interesting results

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doi: 10.1016/j.bbrc.2017.06.031 63 SammsRJCoghlanMPSloopKW

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A significant presence of a GSTP1-1 allelic variant (the GSTP1*C allelic variant) was found in late-onset AD patients 52

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