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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency

doi: 10.1136/gutjnl-2018-318126 30 KalisperatiPSpanouEPaterasISKorkolopoulouPVarvarigouAKaravokyrosIet al

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