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Ma C, Wu J, Chen Y, Zhang D, Zhou D, Zhang J, Yan M (2025) The phytohormone brassinosteroid (BR) promotes early seedling development via auxin signaling pathway in rapeseed
Maridebart cafraglutide (a monthly GLP-1 in trials) addresses this by using an IgG scaffold to harness the natural FcRn recycling pathway for around a two-week half-life
Therapies do not work if not taken properly
There are clear contraindications based on the trial exclusion criteria and the known risks of this drug class
Nausea is very common during dose escalation of GLP-1 therapies according to their SmPCs, and can reduce nutritional intake further and lead to dehydration if accompanied by vomiting
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