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Mahabir, S., Spitz, M

The position of the acetamide group of C1-31 is stabilized by hydrophobic interactions with the side chains of G-site residues L56 and V72

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Moreover, it has been reported that if nanoparticle-based immune cell death inducers (ICD) are coupled with immune checkpoint inhibitors (ICIs), then this synergy can prevent the metastatic potential and relapse of tumors

The optimal therapeutic approach may depend on the specific clinical indication, individual patient factors, availability of different treatment options, and the regulatory framework within the practicing jurisdiction