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1998 Mar 17;95(6):3071-6
Mechanistically, DAMPs interact with toll-like receptors (TLRs) and purinergic receptors on Kupffer cells, resulting in the secretion of pro-inflammatory mediators such as IL-6, IL-18, IFN-, TNF-, and Fas ligands, which further promote macrophage proliferation [54]
Understanding your bodys response is important
Practice parameter for the use of stimulant medications in the treatment of children, adolescents, and adults