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doi: 10.1016/S2213-8587(23)00356-X 13 JastreboffAMKaplanLMFrasJPWuQDuYGurbuzSet al

The trickiest situation happens when a PCP feels unsure about prescribing newer weight loss medications

GLP-1 receptor agonists (including medications like semaglutide, liraglutide, and tripeptide) mimic the action of this natural hormone
Further research into its impact on fat metabolism, appetite regulation, and inflammatory pathways is needed to clarify these observations
Researchers are still determining whether long-term Retatrutide treatment produces cumulative thermogenic benefits or whether tolerance develops over time

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