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The glucagon receptor and corticotropin-releasing factor receptor 1 TM domain structures were solved by x-ray crystallography showing the expected topology of the seven transmembrane -helices 20,21
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We did not elucidate the specific GLP-1R interactions made by N-terminally modified exendin-4 analogs responsible for their marked differences in signaling and trafficking
Front Aging 3:916118
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