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careful riskbenefit assessment is warranted Those with pre-existing gallbladder disease : Rapid weight loss can precipitate gallstone formation or worsen existing biliary conditions People with severe gastrointestinal disease, including gastroparesis : GLP-1 receptor agonists slow gastric emptying, which may worsen symptoms in those with pre-existing gastric motility disorders Older adults : Age-related changes in renal and hepatic function may affect drug metabolism and increase sensitivity to side effects

Grevys, A
Similarly, a neurologist who is specialized for nervous system-related problems can help a patient overcome neurological symptoms, such as sleep disturbance, fatigue, and cognitive and memory problems

Six of the letters sent to outsourcing facilities include a recommendation to engage a third-party consultant with relevant sterile drug manufacturing expertise to assist with a comprehensive evaluation that includes review of aseptic processing techniques
