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Current Phase 2 trial data associate retatrutide with dose-dependent increases in resting heart rate, but no increase in major adverse cardiovascular events was observed
Because of its low IGFBP binding, researchers have noted increased availability of free ligand to target-cell receptors in these model systems compared with native IGF-1
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Phase 3 results are expected in 2025-2026
Hunter and Taylor break down why progesterone is the first building block, how to dose it by symptom relief rather than blood work numbers, and why more women in their 20s and 30s are candidates for testosterone than most people realize
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