Hereditäre Ataxie (HA) - Norwegischer Elchhund All Leukocyte adhesion deficiency (LAD3) is

Leukocyte adhesion deficiency (LAD3) is a rare canine autosomal recessive disorder characterised by failure of activation of beta 1–3 type integrins

impulsive behaviour

The diagnosis is complicated due to normal laboratory test results

Coat color can be diluted in pigmented skin areas

A dog usually carries this gene variant in a hidden form

Hereditäre Ataxie (HA) - Norwegischer Elchhund All Leukocyte adhesion deficiency (LAD3) isAtaxia is a neurodegenerative disease defined by incoordination of voluntary movements. Hereditary ataxia affecting Black Norwegian elkhounds is an early onset disease with symptoms developing from around 4 weeks of age. It is caused by axonal swelling in the cerebellum and abnormalities in the brain stem. The affected dogs show a moderately ataxic walk with the tendency of overstepping, unsteady and broad based pelvic limbs, lack of balance and